phong hoa sinh ung dung 2021

  1. About the Lab

Head: Nguyen Thi Thu Ha

Tel: 02437914586

E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Contact address: Room 601, A18 building, Institute of Chemistry, No. 18 Hoang Quoc Viet street, Cau Giay district, Ha Noi, Vietnam.

  1. Lab members:

Dr. Nguyen Thi Thu  Ha

Dr. Ninh The Son

Dr. Nguyen Thanh Tra

Dr. Le Thi Tu Anh

Master Ba Thi Cham

Master Nguyen Thi Thuy Linh

  1. Research areas:

- Develop and implement the biological activity test in vitro such as antimicrobial activity, cytotoxic activity, antioxidant activity, enzyme inhibitory activity glucosidase (diabetes), acetylcholine (Alzheimer's)

- Research and exploitation of bioactive compounds, converting them into substances that have a high economic value which cater to the pharmaceutical industry.

- Postgraduate training.

4. Publications:

TT

Tên bài báo

Tên tác giả

Tên tạp chí

Năm công bố

1

Cytotoxic and α-Glucosidase Inhibitory Xanthones from Garcinia mckeaniana Leaves and Molecular Docking Study

Nguyen Thi Thu Ha, Ninh The Sơn et al.

Chemistry Biodiversity

 

2021

2

A new cytotoxic compound from the leaves of Styrax annamensis Guillaumin

Nguyen Thanh Tra, Ninh The Sơn et al.

Natural Product Research

 

2021

3

Antioxidative and α-glucosidase inhibitory constituents of Polyscias guilfoylei: experimental and computational assessments

Le Thi Tu Anh, Ninh The Sơn et al.

Molecular Diversity

·         2021

4

Medicinal Plant Centipeda Minima: A Resource of Bioactive Compounds

Nguyen Thi Thuy Linh, Trinh Thi Thuy et al.

Mini Reviews in Medicinal Chemistry 

2021

·         

5

Garcimckeans A-C, three new xanthones from the stems of Garciniamckeaniana, and their cytotoxic activity

Nguyen Thi Thu Ha, Ninh The Sơn et al.

Natural Product Research  

 

2021

6

A New Flavonoid from the Leaves of Garcinia mckeaniana Craib and α-Glucosidase and Acetylcholinesterase Inhibitory Activities

Nguyen Thi Thu Ha, Ninh The Sơn et al.

Natural Product Research  

 

2021

7

Chemical constituents from the leaves of Styrax argentifolius H.L. Li and their biological activities

Nguyen Thanh Tra, Ninh The Sơn et al.

Phytochemistry Letters 

2021

8

Chemical constituents from the leaves of Styrax argentifolius H.L. Li and their antioxidative activity

Nguyen Thanh Tra, Ninh The Sơn et al.

Discovery Phytomedicine 

2021

9

Quinolone and isoquinolone alkaloids: The structural-electronic effects and the antioxidant mechanisms, Structural Chemistry

Nguyen Tien Dung, Ninh The Sơn et al.

Structural Chemistry

2020

10

Vasorelaxing activity of R-(-)-3'-hydroxy-2,4,5-trimethoxydalbergiquinol from Dalbergia tonkinensis Prain: Involvement of smooth muscle Cav1.2 channels

Nguyễn Mạnh Cường, Ninh The Sơn et al.

Planta medica

2020

11

Antioxidant of 2-Phenylbenzofuran derivatives: Structural-Electronic Effects and Mechanisms

Phan Thi Thuy, Ninh The Sơn et al.

RSC Advances 

2020

12

Cell Growth Inhibition of Saponin XII from Dipsacus japonicus Miq. on Acute Myeloid Leukemia Cells

Ba Thi Cham, Nguyen Thi Thuy Linh, Do Thi Thao, Nguyen Thi Hoang Anh,

Nguyen Thanh Tam, Bui Kim Anh, Isabella Muscari, Sabrina Adorisio, Tran Van Sung,

Trinh Thi Thuy and Domenico V. Delfino

Molecules

2020

13

Cytotoxic naphthoquinones from Diospyros fleuryana leaves

Nguyen Thi Thu Ha, Ninh The Sơn et al.

Discovery Phytomedicine

 

2020

14

Antioxidant Constituents from the Stem and Leaf of Helicteres hirsuta Loureiro

Nguyen Thanh Tra, Ninh The Sơn et al.

The Natural Products Journal

 

2020

15

Chemical constituents of Peltophorum pterocarpum stems

Ba Thi Cham, Trinh Thi Thuy et al.

Vietnam Journal of Chemistry

2020

16

Chemical constituents from the leaves of Styrax annamensis Guill

Nguyen Thanh Tra, Ninh The Sơn et al.

Vietnam Journal of Chemistry 

2020

17

Cytotoxic naphthoquinones from Diospyros fleuryana leaves

Nguyen Thi Thu Ha, Ninh The Sơn et al.

Discovery Phytomedicine,

2020

18

Chemical constituents from methanolic extract of Garcinia mackeaniana leaves and their antioxydant activity

Nguyen Thi Thu Ha, Ninh The Sơn et al.

Vietnam Journal of Science and Technology

2020

19

Antimicrobacterial xanthones from Garcinia mackeaniana leaves

Nguyen Thi Thu Ha, Ninh The Sơn et al.

Vietnam journal of chemistry

2020

20

In vitro alpha glucosidase and acetylcholinesterase enzyme inhibitory from leaves of Diospyros fleuryana

Nguyen Thi Thu Ha, et al.

Vietnam journal of chemistry

2020

21

Phenolic acid analogues from Balanophora laxiflora inhibit proliferation of in vitro acute myeloid leukemia cells.

Trinh Thi Thuy, Ba Thi Cham, Nguyen Thi Thuy Linh, Phan Thi Ngoc Bich, Sabrina Adorisio and Domenico V Delfino.

Rec. Nat. Prod.

2021

22

Chemical constituents of Impatiens chapaensis Tard. and their α-glucosidase inhibition activities.

Nguyen Thi Thuy Linh, Trinh Thi Thuy, Nguyen Thanh Tam, Ba Thi Cham, Khieu Thi Tam, Nguyen Hoang Sa, Do Thi Thao, Vu Tien Chinh, Nguyen Thi Hoang Anh

Natural product research

2021

23

Study on chemical constituents and biological activity of Heterostemma glandiflorum Cost. (Nghiên cứu thành phần hóa học và hoạt tính sinh học cây Dị hùng hoa to)

Khiếu Thị Tâm, Nguyễn Thị Thùy Linh, Lê Thị Hồng Nhung, Nguyễn Thanh Tâm, Nguyễn Thị Hoàng Anh

Tạp chí Khoa học Công nghệ (ĐH Công nghiệp Hà Nội)

2020

24

Qualitative and quatitative analysis of flavonoid in in Artocarpus tonkinensis leaves by high performance liquid chromatography-mass spectrometry (HPLC-MS).

Nguyen Thi Thuy Linh, Ba Thi Cham, Nguyen Thi  Hoang Anh, Tran Duc Quan, Dao Duc Thien, Nguyen Thanh Tam, Bui Kim Anh, Do Quoc Viet, Le Thi Hong Nhung, Domenico V. Delfino, Trinh Thi Thuy

Tạp chí Khoa học Công nghệ (ĐH Công nghiệp Hà Nội)

2020

25

Chemical constituents of Peltophorum pterocarpum stems

Ba Thi Cham, Nguyen Thi Thuy Linh, Nguyen Thi Hoang Anh, Tran Duc Quan,

Nguyen Thanh Tam, Dao Duc Thien, Le Thi Hong Nhung, Tran Van Sung, Ninh The Son, Domenico V. Delfino, Vu Dinh Hoang, Trinh Thi Thuy

Vietnam Journal of Chemistry

2020

26

Ecdysteroids from Vitex leptobotrys inhibit proliferation of acute myeloid leukemia cells.

Nguyen Thi Thuy Linh, Ba Thi Cham, Nguyen Thi Hoang Anh, Nguyen Thanh Tam, Dao Duc Thien, Tran Duc Quan, Tran Van Sung, Sabrina Adorisio, Domenico V Delfino, Trinh Thi Thuy.

Tạp chí hóa học

2019

27

New phenolics from Dianella ensifolia

Le Thi Hong Nhung, Nguyen Thi Thuy Linh, Ba Thi Cham, Trinh Thi Thuy, Nguyen Thanh Tam, Dao Duc Thien, Pham Thi Mai Huong, Vu Minh Tan, Bui Huu Tai & Nguyen Thi Hoang Anh

Natural Product Research

2019

28

Pro-apoptoticeffect of diterpenoids from Fokienia hodginsii on acute myeloid leukemia cells.

Dang Viet Hau, Nguyen Hoang Sa, Nguyen Thanh Tam, Nguyen Thi Diep, Nguyen Thi Hoang Anh, Nguyen Thi Thuy Linh, Huynh Thi Ngoc Ni, Sabrina Adorisio, Domenico V. Delfino & Trinh Thi Thuy.

Natural products research

2019

29

Hoạt tính ức chế tăng sinh tế bào bạch cầu tủy xương cấp tính của các hợp chất coumarin tách từ cây hồng bì dại (Clausena excavata).

Bá Thị Châm, Đỗ Thị Thảo, Nguyễn Thị Thùy Linh, Nguyễn Thị Hoàng Anh, Nguyễn Thanh Tâm, Sabrina Adorisio, Trần Văn Sung, Domenico V Delfino, Trịnh Thị Thủy.

Tạp chí hóa học

2019

30.

Antiproliferative activity of isolated compounds from pinus dalatensis and Pinus krempfii on acute myeloid leukemia cells.

Nguyen Hoang Sa, Nguyen Thanh Tam, Tran Duc Quan, Nguyen Thi Hoang Anh, Nguyen Thi Thuy Linh, Le Thi Hong Nhung, Sabrina Adorisio, Domenico V Delfino, Tran Van Sung, Trinh Thi Thuy.

Vietnam Journal of Chemistry

2019

 

  1. International cooperation

  • Tibotec pharmaceutical company, Belgium

  • University of Copenhagen, Denmark.

     -    Institute of Organic Chemistry – Russian Academy of Sciences

Bài viết khác: